Regional droughts in the Caribbean are common. Water managers seeking solutions to water scarcity are often unfamiliar with the option of using water-from-air technology. Maps of the specific humidity composite mean for Junes and Decembers during the ten-year period 2004–2013 quantify the water-from-air resource demonstrating it is suitable for operation of water-from-air systems in Caribbean countries. Quantitative investigations by the author found droughts and long-term climate change do not appear to affect the magnitude of the Caribbean region’s water-from-air resource. Case studies include one for a proposed water-from-air commercial greenhouse on Grand Turk. Another case is about the experience of commissioning a 2500 L/d water-from-air machine in Belize City. Lessons learned from the case studies are outlined.